Ruihong Jiang

Title: Ruihong Jiang - Innovator in Biomedicine

Introduction

Ruihong Jiang is a prominent inventor based in Suzhou, China. He has made significant contributions to the field of biomedicine, particularly in the development of vaccines and therapeutic agents.

Latest Patents

Ruihong Jiang holds a patent for "Mutants of respiratory syncytial virus fusion proteins." This patent focuses on an improved mutant of the respiratory syncytial virus (RSV) fusion (F) protein. The innovation allows the mutant to form a trimeric structure without the need for a heterologous trimerization domain. Through various mutation designs, such as releasing internal electrostatic repulsion and deleting the furin cleavage site, the protein is stabilized in its pre-fusion conformation. This enhanced stability makes the mutant highly immunogenic, capable of inducing a high level of neutralizing antibodies in immunized animals. The mutant can be utilized in vaccine preparation for the prevention or treatment of RSV infection and serves as a reagent for RSV detection.

Career Highlights

Ruihong Jiang is associated with Yikang Biotech (Suzhou) Co., Ltd., where he continues to advance his research and innovations in biomedicine. His work has garnered attention for its potential impact on public health.

Collaborations

Ruihong Jiang collaborates with notable colleagues, including Lei Chen and Yujiao Song, contributing to a dynamic research environment that fosters innovation.

Conclusion

Ruihong Jiang's work in developing mutants of RSV fusion proteins exemplifies the critical role of inventors in advancing medical science. His contributions are paving the way for new vaccine strategies and therapeutic options.