Company Filing History:
7 out of 1,211 
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Years Active: 2012-2022
Title: The Innovative Contributions of Ruben Carrasco
Introduction
Ruben Carrasco is a notable inventor based in Brookline, MA (US), recognized for his significant contributions to the field of cancer research. With a total of seven patents to his name, Carrasco has made strides in developing therapeutic methods for treating multiple myeloma and other hematological malignancies.
Latest Patents
One of Carrasco's latest patents is focused on "Compositions and methods for treating multiple myeloma." This invention provides methods for identifying therapeutic agents for treating multiple myeloma, as well as for determining the prognosis of patients with this condition. The methods are based on the discovery that an extracellular form of cyclophilin A binds to CD147 expressed on multiple myeloma cells.
Another significant patent is titled "Targeting deregulated Wnt signaling in cancer using stabilized alpha-helices of BCL-9." This invention offers structurally-constrained peptides created through hydrocarbon stapling of a BCL9 HD2 helix for therapeutic use. The invention demonstrates that these hydrocarbon-stapled helical peptides exhibit excellent stability and superior pharmacokinetic properties, effectively disrupting the BCL9/β-catenin interaction, which is crucial for therapeutic benefits in various human diseases, including cancer.
Career Highlights
Throughout his career, Ruben Carrasco has worked with esteemed organizations such as Dana-Farber Cancer Institute Inc. and the University of Arkansas. His work in these institutions has allowed him to contribute to groundbreaking research in cancer treatment and therapeutic development.
Collaborations
Carrasco has collaborated with prominent figures in the field, including Ronald A. DePinho and Kenneth Carl Anderson. These collaborations have further enhanced his research and innovation in cancer therapies.
Conclusion
Ruben Carrasco's innovative work and patents have significantly advanced the understanding and treatment of multiple myeloma and other cancers. His contributions continue to impact the field of medical research and therapeutic development.