The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 13, 2016
Filed:
Apr. 14, 2015
Applicant:
Dana-farber Cancer Institute, Inc., Boston, MA (US);
Inventors:
Ruben Carrasco, Brookline, MA (US);
Jianjun Zhao, Brookline, MA (US);
Assignee:
DANA-FARBER CANCER INSTITUTE, INC., Boston, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 48/00 (2006.01); C07H 21/02 (2006.01); C07H 21/04 (2006.01); C12Q 1/68 (2006.01); C12N 15/113 (2010.01); A61K 45/06 (2006.01); A61K 9/14 (2006.01); A61K 9/00 (2006.01); A61K 31/7105 (2006.01); A61K 31/711 (2006.01); A61K 31/663 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/6886 (2013.01); A61K 9/0019 (2013.01); A61K 9/145 (2013.01); A61K 31/663 (2013.01); A61K 31/711 (2013.01); A61K 31/7105 (2013.01); A61K 45/06 (2013.01); C12N 15/113 (2013.01); C12N 15/1135 (2013.01); C12N 2310/14 (2013.01); C12N 2310/141 (2013.01); C12N 2310/321 (2013.01); C12N 2320/31 (2013.01); C12Q 2600/118 (2013.01); C12Q 2600/178 (2013.01);
Abstract
Provided are compositions and methods for treating hematological malignancies, such as multiple myeloma, in a subject by increasing levels or activity of miR-30 RNA in plasma cells of the subject.