The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 12, 2016

Filed:

May. 17, 2012
Applicants:

Ronald A. Depinho, Houston, TX (US);

Kenneth C. Anderson, Wellesley, MA (US);

Ruben D. Carrasco, Brookline, MA (US);

Giovanni Tonon, Cernusco sul Naviglio, IT;

Cameron Brennan, Haworth, NJ (US);

John D. Shaughnessy, Jr., Roland, AR (US);

Lynda Chin, Houston, TX (US);

Inventors:

Ronald A. DePinho, Houston, TX (US);

Kenneth C. Anderson, Wellesley, MA (US);

Ruben D. Carrasco, Brookline, MA (US);

Giovanni Tonon, Cernusco sul Naviglio, IT;

Cameron Brennan, Haworth, NJ (US);

John D. Shaughnessy, Jr., Roland, AR (US);

Lynda Chin, Houston, TX (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/574 (2006.01); C12Q 1/68 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/6837 (2013.01); C12Q 1/6841 (2013.01); C12Q 1/6886 (2013.01); C12Q 2600/106 (2013.01); C12Q 2600/118 (2013.01); C12Q 2600/136 (2013.01); C12Q 2600/178 (2013.01);
Abstract

The invention relates to compositions, kits, and methods for detecting, characterizing, preventing, and treating human cancer. A variety of chromosomal regions (MCRs) and markers corresponding thereto, are provided, wherein alterations in the copy number of one or more of the MCRs and/or alterations in the amount, structure, and/or activity of one or more of the markers is correlated with the presence of cancer.


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