Location History:
- Wilmington, DE (US) (1993)
- Macclesfield, GB (1995 - 1998)
Company Filing History:
Years Active: 1993-1998
Title: Innovations by Royston M Thomas: Pioneering Patents in Medicinal Chemistry
Introduction
Royston M Thomas, an accomplished inventor based in Macclesfield, GB, has made significant contributions to the field of medicinal chemistry. With a portfolio of six patents, Thomas has focused on developing compounds that hold promise in treating diseases linked to human leukocyte elastase (HLE), enhancing research tools in pharmacology and diagnostics.
Latest Patents
Thomas's most recent patents include innovative compounds known as 1-pyrimidinylacetamide derivatives. These compounds are designed to act as inhibitors of human leukocyte elastase (HLE), also referred to as human neutrophil elastase (HNE). The primary application of these inhibitors is in pharmacological and diagnostic studies, and they potentially play a crucial role in the treatment of diseases in mammals where HLE is implicated.
Additionally, he has developed novel heterocyclic ketones, which are classified as 1-pyridylacetamide ketones. Similar to his previous work, these ketones serve as inhibitors of HLE, proposing their use in both research and therapeutic contexts. The inventions also encompass various intermediates that can facilitate the synthesis of these derivatives, processes for their preparation, pharmaceutical compositions containing them, and methods for their application.
Career Highlights
Throughout his career, Royston M Thomas has collaborated with prominent companies in the pharmaceutical industry, including Zeneca Limited and Imperial Chemical Industries Limited. His experience in these forefront organizations has enabled him to advance his research and patenting capabilities in medicinal chemistry.
Collaborations
During his career, Thomas has worked alongside notable colleagues such as Peter R Bernstein and Peter Warner. These associations have likely contributed to the enriched knowledge and innovative ideas that Thomas brings to his work.
Conclusion
Royston M Thomas stands out as a notable figure in the domain of patent innovation, particularly in the development of compounds targeting human leukocyte elastase. His work not only contributes to medical science but also showcases the significant impact of research and innovation in improving health outcomes. With six patents to his name, Thomas continues to pave the way for further advancements in the field.