Roxana G Baluna

Title: The Innovative Contributions of Roxana G Baluna

Introduction

Roxana G Baluna is a prominent inventor based in San Antonio, TX (US). She has made significant contributions to the field of immunology and vaccine development. With a total of 6 patents to her name, her work focuses on creating safer and more effective vaccines against various toxins.

Latest Patents

One of her latest patents is titled "Ricin A chain mutants lacking enzymatic activity as vaccines to protect against aerosolized ricin." This invention provides methods to produce toxoid vaccines, such as ricin A chain vaccines, with a reduced ability to promote vascular leak syndrome (VLS) and catalytic toxicity associated with various proteinaceous toxins. The invention also includes toxoids that have been mutated to lack amino acid sequences which induce VLS and toxic catalytic activity. Another significant patent is "Compositions and methods for modifying toxic effects of proteinaceous compounds." This invention outlines methods to produce immunotoxins (ITs) and cytokines with a reduced ability to promote VLS. It also discloses ITs and cytokines that have been mutated to lack amino acid sequences which induce VLS, along with methods for producing peptides that inhibit the induction of VLS by ITs and cytokines.

Career Highlights

Roxana G Baluna is affiliated with the University of Texas System, where she continues her research and development efforts. Her innovative work has garnered attention in the scientific community, contributing to advancements in vaccine technology.

Collaborations

Throughout her career, Roxana has collaborated with notable colleagues, including Ellen S Vitetta and Victor F Ghetie. These collaborations have further enhanced her research and the impact of her inventions.

Conclusion

Roxana G Baluna's contributions to the field of immunology and vaccine development are noteworthy. Her innovative patents reflect her commitment to improving public health through safer vaccine technologies.