Company Filing History:
Years Active: 2022-2023
Title: Ross Wadsworth: Innovator in Nucleic Acid Technologies
Introduction
Ross Wadsworth is a notable inventor based in Cape Town, South Africa. He has made significant contributions to the field of molecular biology, particularly in the development of advanced nucleic acid technologies. With two patents to his name, Wadsworth's work has the potential to enhance the accuracy and efficiency of genetic research.
Latest Patents
Wadsworth's latest patents include innovations that focus on reverse transcriptase variants and nucleic acid library preparation. The first patent, titled "Reverse transcriptase variants," presents MMLV reverse transcriptase enzymes that exhibit increased thermal stability compared to wild type MMLV and AMV reverse transcriptases. This improvement allows for reverse transcription of RNA to cDNA at temperatures exceeding 37°C, thereby reducing error rates during cDNA synthesis. The enhanced accuracy of these reverse transcriptases facilitates more reliable determination of transcriptomes in living organisms.
The second patent, "System and method for nucleic acid library preparation via template switching mechanism," discloses a composition that includes a double-stranded deoxyribonucleic acid (dsDNA) sequence. This sequence comprises a first adaptor sequence, a template sequence, and a second adaptor sequence, which contains a hybridization site for a template switching oligonucleotide (TSO). The methods outlined in this patent utilize a template switching mechanism to add non-templated base pairs to the ends of a DNA molecule, allowing for the hybridization of a TSO and subsequent extension of the sequence.
Career Highlights
Throughout his career, Wadsworth has worked with prominent companies in the biotechnology sector, including Watchmaker Genomics, Inc. and Kapa Biosystems, Inc. His experience in these organizations has contributed to his expertise in nucleic acid technologies and innovation.
Collaborations
Wadsworth has collaborated with notable professionals in his field, including Julie Walker and Bjarne Faurholm. These collaborations have likely enriched his research and development efforts, fostering a collaborative environment for innovation.
Conclusion
Ross Wadsworth is a distinguished inventor whose work in nucleic acid technologies has the potential to significantly impact genetic research. His patents reflect a commitment to enhancing the accuracy and efficiency of molecular biology techniques.