Location History:
- New York, NY (US) (2007 - 2011)
- Tuckahoe, NY (US) (2015 - 2016)
Company Filing History:
4 out of 1,697 
1 out of 44 
1 out of 976 Years Active: 2007-2016
Title: Ross N Chapman: Innovator in Peptide Research and Therapeutic Development
Introduction: Ross N Chapman, based in Tuckahoe, NY, is a distinguished inventor with a focus on peptide research and its applications in pharmaceuticals. With a total of five patents to his name, he has contributed significantly to the field of biotechnology through cutting-edge innovations aimed at addressing various health challenges.
Latest Patents: Among his notable patents, the latest invention titled "Inhibiting interaction between the HIF-1ALPHA and p300/CBP with hydrogen bond surrogate-based helices" presents a groundbreaking advancement. This invention centers around peptides that possess stable, internally constrained α-helices, which mimic sections of the C-terminal transactivation domain of HIF-1α. The pharmaceutical compositions derived from these peptides offer methods for reducing gene transcription and treating disorders linked to the interaction of HIF-1α with CREB-binding protein and p300. Additionally, the invention aims to prevent angiogenesis, induce apoptosis, and decrease cell survival or proliferation. Another significant patent involves methods for preparing these internally constrained peptides and peptidomimetics that enhance the stability of α-helical and β-sheet structures within peptide designs.
Career Highlights: Ross N Chapman's career includes pivotal roles at institutions like New York University and Aileron Therapeutics, Inc. His work in these organizations reflects his commitment to advancing peptide therapeutics and exploring their potential in treating complex diseases.
Collaborations: Throughout his professional journey, Ross has collaborated with esteemed colleagues, including Paramjit S Arora and Bogdan Z Olenyuk. These partnerships have been instrumental in furthering his research and the practical applications of his inventions in the biomedical field.
Conclusion: With a robust portfolio of patents and a proven track record in peptide research, Ross N Chapman continues to be a beacon of innovation. His contributions not only advance scientific knowledge but also hold promise for the development of new therapeutic strategies to tackle pressing health issues.