Company Filing History:
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Years Active: 2013-2021
Title: Roslyn Bernstein Mannon: Innovator in Transplant Medicine
Introduction
Roslyn Bernstein Mannon is a distinguished inventor based in Birmingham, AL (US). He has made significant contributions to the field of transplant medicine, holding 2 patents that focus on innovative methods for detecting graft rejection and assessing transplant glomerulopathy.
Latest Patents
One of Mannon's latest patents is titled "Urine biomarkers for detecting graft rejection." This invention provides compositions, systems, kits, and methods for detecting rejection or an elevated risk of rejection of an organ or tissue graft, such as a kidney graft. The method involves detecting one or a panel of RNA markers in a urine sample from the subject. In certain embodiments, kidney graft injury is identified by measuring specific RNA markers, which can help distinguish between acute graft rejection and BK virus nephropathy.
Another notable patent is the "Bayesian clinical decision model for determining probability of transplant glomerulopathy." This invention outlines a method for determining a patient-specific probability of transplant glomerulopathy. It involves collecting clinical parameters from multiple patients to create a training database. A fully unsupervised Bayesian Belief Network model is then developed and validated using this data. Clinical parameters from individual patients are input into the model, which outputs the patient-specific probability of transplant glomerulopathy for use by clinicians in pre-operative planning.
Career Highlights
Mannon has worked with prominent organizations, including the U.S. Government as represented by the Secretary of the Army and the Cleveland Clinic Foundation. His work in these institutions has allowed him to contribute to advancements in medical technology and patient care.
Collaborations
Throughout his career, Mannon has collaborated with notable professionals, including Alexander Stojadinovic and Eric Elster. These collaborations have further enriched his research and innovations in the field of transplant medicine.
Conclusion
Roslyn Bernstein Mannon is a pioneering inventor whose work has significantly impacted transplant medicine. His patents reflect a commitment to improving patient outcomes through innovative detection methods and clinical decision-making tools.