The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 06, 2026

Filed:

Jun. 01, 2021
Applicants:

The Cleveland Clinic Foundation, Cleveland, OH (US);

The Uab Research Foundation, Birmingham, AL (US);

Inventors:

Robert L. Fairchild, Mayfield Village, OH (US);

Roslyn Bernstein Mannon, Birmingham, AL (US);

Assignees:

The Cleveland Clinic Foundation, Cleveland, OH (US);

The UAB Research Foundation, Birmingham, AL (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/68 (2018.01); C12Q 1/6883 (2018.01); C12Q 1/70 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/6883 (2013.01); C12Q 1/701 (2013.01); C12Q 2600/158 (2013.01);
Abstract

Provided herein are compositions, systems, kits, and methods for detecting rejection, or an elevated risk of rejection, of an organ or tissue graft (e.g., kidney graft) in a subject by detecting one, or a panel of, RNA markers in a urine sample from the subject. In certain embodiments, kidney graft injury is detected by measuring one or more of the RNA markers disclosed herein. In some embodiments, the one or more markers are employed to distinguish between acute graft rejection and BK virus nephropathy.


Find Patent Forward Citations

Fairchild, Robert. (2026). Urine biomarkers for detecting graft rejection (U.S. Patent No. 12516377). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12516377

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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