Company Filing History:
Years Active: 2021-2024
Title: Innovator Spotlight: Rosemarie Kuehn
Introduction
Rosemarie Kuehn, an accomplished inventor based in St. Louis, MO, has made significant contributions to the field of genetic modification through her innovative patents. With a total of three patents, Kuehn is recognized for her work in advancing agricultural biotechnology, particularly in plant genetics.
Latest Patents
Kuehn's latest patent revolves around "Compositions and methods for site-directed genomic modification." This patent presents novel promoters derived from corn, tomato, and soybean plants, specifically U6, U3, U2, U5, and 7SL snRNA promoters. These are essential for CRISPR/Cas-mediated targeted gene modifications in plants. The patent also highlights methods for utilizing these promoters to drive the expression of sgRNA polynucleotides, which are pivotal in the CRISPR/Cas system for targeted gene modification. Additionally, it outlines methods for genome modification through the insertion of blunt-end DNA fragments at genomic cleavage sites, further enhancing precision in genetic engineering.
Career Highlights
Kuehn's professional journey is marked by her role at Monsanto Technology LLC, where she has collaborated on groundbreaking research in the realm of plant genetics. Her innovative approaches have paved the way for new methodologies in crop improvement and genetic modification, solidifying her place in the field.
Collaborations
Throughout her career, Kuehn has worked alongside notable colleagues such as Brent Brower-Toland and Andrei Y Kouranov. These collaborations have allowed for the amalgamation of diverse expertise, driving advancements in agricultural biotechnology and the effective application of CRISPR technology.
Conclusion
Rosemarie Kuehn's contributions to the field of genetic modification demonstrate her commitment to innovation and excellence. Her work not only impacts the agricultural sector but also sets the stage for future advancements in plant genetics. With her impressive track record of patents and collaborations, Kuehn remains a prominent figure in the world of biotechnology.