Company Filing History:
Years Active: 2003-2007
Title: The Innovative Contributions of Ronald H Chiarello
Introduction
Ronald H Chiarello is a notable inventor based in Castro Valley, California. He has made significant contributions to the field of oligonucleotide labeling, holding a total of three patents. His work has advanced the methodologies used in the synthesis of labeled oligonucleotides, which are crucial in various scientific applications.
Latest Patents
Chiarello's latest patents include innovative techniques and compositions for labeling oligonucleotides. One of his patents describes a novel method for the economical synthesis of 5' labeled molecules. This method utilizes a carefully selected set of amino linkers and a modified deprotination/cleavage protocol, allowing for the convergent synthesis of multiple labeled oligonucleotides. Another significant patent involves rhodamine-based fluorophores, which are fluorescent dyes derivatized to form labeled conjugates. These conjugates fluoresce upon excitation with light of an appropriate wavelength, enhancing the efficiency of synthesizing rhodamine-labeled oligonucleotides through solid-phase methods.
Career Highlights
Throughout his career, Ronald H Chiarello has worked with prominent companies such as Syngen, Inc. and BASF Aktiengesellschaft. His experience in these organizations has contributed to his expertise in the field of chemical synthesis and labeling techniques.
Collaborations
Chiarello has collaborated with notable colleagues, including Wing Liu and Kathy Yokobata. These partnerships have likely fostered innovation and the exchange of ideas in their respective fields.
Conclusion
Ronald H Chiarello's contributions to the field of oligonucleotide labeling through his patents and collaborations highlight his role as an influential inventor. His work continues to impact scientific research and development in significant ways.