Company Filing History:
Years Active: 2009-2010
Title: Innovations in Oxazole Production by Inventor Rolf-Ludwig Hoerlein
Introduction
Rolf-Ludwig Hoerlein, based in Frankfurt-am-Main, Germany, is a notable inventor with a notable contribution to the field of organic chemistry. He holds two patents focusing on the production of oxazoles, which serve as critical intermediates in pharmaceutical development.
Latest Patents
Hoerlein’s latest patents include:
1. **Method for the production of oxazoles by condensing aromatic aldehydes with α-ketoximes to N-oxides and then reacting the same with activated acid derivatives.** This invention details a process for preparing compounds utilizing aromatic aldehydes through a series of conversions, resulting in halomethyloxazoles of high purity.
2. **Method for the preparation of oxazoles by condensing aromatic aldehydes with α-ketoximes to form N-oxides and reacting the same with activated acid derivatives.** This patent presents an improved method that enhances the yield of oxazoles while minimizing impurities and contaminants. Oxazoles are valuable for their role in synthesizing pharmaceutically active substances, including PPAR agonists, influential in lipid and glucose metabolism.
Career Highlights
Rolf-Ludwig Hoerlein is currently employed at Sanofi-Aventis Deutschland GmbH, where his research significantly contributes to the company's pharmaceutical innovations. His expertise in organic synthesis and dedication to improving chemical processes underline his impactful career.
Collaborations
Throughout his professional journey, Hoerlein has collaborated with esteemed colleagues, including Wolfgang Holla and Berndt Kulitzscher. These collaborations have strengthened the innovative environment within which he works, fostering advancements in pharmaceutical chemistry.
Conclusion
Rolf-Ludwig Hoerlein's contributions to the synthesis of oxazoles exemplify the intersection of scientific research and practical applications in pharmaceuticals. His work enhances not only the understanding of organic reactions but also paves the way for developing new therapeutic agents that positively impact human health.
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