The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 09, 2009

Filed:

May. 29, 2007
Applicants:

Wolfgang Holla, Kelkheim, DE;

Rolf-ludwig Hoerlein, Frankfurt, DE;

Berndt Kulitzscher, Esselbach, DE;

Wolfgang Laux, Sceaux, FR;

Thomas Stuedemann, Kelkheim, DE;

Christoph Tappertzhofen, Frankfurt, DE;

Robert J. H. Scheffer, Ingelheim, DE;

Inventors:

Wolfgang Holla, Kelkheim, DE;

Rolf-Ludwig Hoerlein, Frankfurt, DE;

Berndt Kulitzscher, Esselbach, DE;

Wolfgang Laux, Sceaux, FR;

Thomas Stuedemann, Kelkheim, DE;

Christoph Tappertzhofen, Frankfurt, DE;

Robert J. H. Scheffer, Ingelheim, DE;

Assignee:

Sanofi-Aventis Deutschland GmbH, Frankfurt am Main, DE;

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 263/32 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention is comprised of improved methods in the preparation of oxazoles which results in higher yields with less impurities and contaminants. Oxazoles constitute valuable intermediates in the synthesis of pharmaceutically active substances such as, for example peroxisome proliferator activated receptor (PPAR) agonists which are pharmaceutical actives which can have a positive influence on both lipid and glucose metabolism.


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