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For the Inventor, By the Inventor

King of Prussia, PA, United States of America

Roland Ellwood Dolle

This inventor holds 81 USPTO granted patents and 1 EPO patent, primarily in Pharmaceutical Chemistry (CPC class C07D-). Top assignees: Adolor Corporation, Pharmacopeia Inc., Vertex Pharmaceuticals, Inc.. Active years: 1995-2015.

IDiyas Innovation Intelligence. (2026). Inventor Profile: Roland Ellwood Dolle. Retrieved from https://idiyas.com/inventor/roland-ellwood-dolle

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

Calculating rank
USPTO Granted Patents = 81

% Patents Active = 56.8

 

Average Co-Inventor Count = 3.5

ph-index = 16

Forward Citations = 591(Granted Patents)

Forward Citations (Not Self Cited) = 549(Dec 10, 2025)


Inventors with similar research interests:

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Location History:

  • Pottstown, PA (US) (1996 - 1997)
  • King of Prussia, PA (US) (1995 - 2013)
  • Hopkinton, MA (US) (2013 - 2015)
  • Ashland, MA (US) (2014 - 2015)

Company Filing History:

goldMedal29 out of 69 
 
Adolor Corporation
 patents
silverMedal17 out of 101 
 
Pharmacopeia Inc.
 patents
bronzeMedal10 out of 1,168 
 
Vertex Pharmaceuticals, Inc.
 patents
4. 8 out of 52 
 
Pharmacopeia Drug Discovery, Inc.
 patents
5. 7 out of 100 
 
Berlex Laboratories, Inc.
 patents
6. 7 out of 206 
 
Sterling Winthrop Inc.
 patents
7. 3 out of 1,549 
 
Sanofi
 patents
8. 2 out of 59 
 
Cubist Pharmaceuticals, Incorporated
 patents
9. 1 out of 16 
 
Sanofi Winthrop Inc.
 patents
10. 1 out of 2,198 
 
Smithkline Beecham Corporation
 patents
11. 3 out of 834,601 
Other
 patents
where one patent can have more than one assignee

Years Active: 1995-2015

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Areas of Expertise:
Beta-Lactamase Inhibitors
Opioid Antagonists
Piperidine Compounds
Spirocyclic Derivatives
Pain Treatment
N-Heterocyclic Derivatives
Phenyl Derivatives
Amide Derivatives
Bicyclic Carboxamide Derivatives
81 patents (USPTO):Explore Patents
1. 9108966 - Beta-lactamase inhibitors (2015-08-18),
2. 8969570 - Beta-lactamase inhibitors (2015-03-03),
3. 8895560 - Opioid antagonists (2014-11-25),
4. 8580788 - Opioid antagonists (2013-11-12),
5. 8404693 - Substituted piperidine compounds and methods of their use (2013-03-26),
6. 8288546 - Substituted piperidine compounds and methods of their use (2012-10-16),
7. 8278323 - Opioid antagonists (2012-10-02),
8. 8071611 - Spirocyclic heterocyclic derivatives and methods of their use (2011-12-06),
9. 8022060 - Spirocyclic heterocyclic derivatives and methods of their use (2011-09-20),
10. 7906646 - Spirocyclic heterocyclic derivatives and methods of their use (2011-03-15),
11. 7884102 - Substituted piperidine compounds and methods of their use (2011-02-08),
12. 7829576 - Beloxepin and analogs for the treatment of pain (2010-11-09),
13. 7820827 - Substituted piperidine compounds and methods of their use (2010-10-26),
14. 7767814 - Substituted piperidine compounds and methods of their use (2010-08-03),
15. 7671052 - Phenyl derivatives and methods of use (2010-03-02),

As an AI assistant specializing in innovations, inventions, inventors, patent attorneys, assignees, and patents, I can provide you with the article about inventor Roland Ellwood Dolle.

Title: The Innovative Journey of Roland Ellwood Dolle

Introduction:

Roland Ellwood Dolle is a prolific inventor based in King of Prussia, PA (US). With an impressive track record of 81 patents to his name, he has made significant contributions to the field of pharmaceuticals and healthcare.

Latest Patents:

One of Dolle's groundbreaking inventions includes Beta-lactamase inhibitors - Aryl substituted diazabicyclooctanes (DBO) compounds that inhibit β-lactamases of class A, class C, or class D and potentiate β-lactam antibiotics. These compounds have shown exceptional efficacy with a minimal inhibitory concentration (MIC) of 8 μg/mL or less against isogenic β-lactamase-expressing bacterial strains.

Career Highlights:

Throughout his career, Dolle has been associated with renowned companies such as Adolor Corporation and Pharmacopeia Inc., where he has spearheaded research and development initiatives aimed at addressing critical healthcare challenges.

Collaborations:

Dolle has collaborated closely with accomplished professionals in the industry, including Bertrand Le Bourdonnec and Stanley J Schmidt. These collaborations have led to the successful development and commercialization of innovative pharmaceutical solutions.

Conclusion:

Roland Ellwood Dolle's inventive spirit and dedication to advancing healthcare through his patented inventions have solidified his reputation as a pioneer in the field. His relentless pursuit of scientific excellence continues to inspire future generations of inventors and researchers.

If you have any more requests or need additional information, feel free to ask.

Profile summary based on public USPTO records.
Data Sources: USPTO Patent Grant XML, Patent Center, EPO & CIPO • Normalized by IDiyas Innovation Graph. Methodology & provenance architecturePlease report any incorrect information to [email protected]
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