Company Filing History:
Years Active: 2005
Title: Roland E Dolle, III: Innovator in Bradykinin B1 Receptor Antagonists
Introduction
Roland E Dolle, III is a notable inventor based in King of Prussia, Pennsylvania. He has made significant contributions to the field of pharmacology, particularly in the development of compounds that target bradykinin receptors. His work has implications for treating various diseases associated with inappropriate bradykinin receptor activity.
Latest Patents
Dolle holds a patent for "Bradykinin B1 receptor antagonists." This patent discloses bradykinin B-receptor antagonists of specific formulas. The compounds are particularly useful for treating diseases such as diabetic vasculopathy, inflammation, pain, hyperalgesia, asthma, rhinitis, septic shock, atherosclerosis, and multiple sclerosis. The patent emphasizes the use of pyrimidines, triazines, and anilines, with a preference for compounds where Q is imidazolyl or pyrrolyl.
Career Highlights
Throughout his career, Dolle has worked with prominent companies in the pharmaceutical industry. He has been associated with Pharmacopeia Drug Discovery, Inc. and Adolor Corporation. His experience in these organizations has contributed to his expertise in drug discovery and development.
Collaborations
Dolle has collaborated with notable professionals in his field, including Michael H J Ohlmeyer and John J Baldwin. These collaborations have likely enhanced his research and development efforts in pharmacology.
Conclusion
Roland E Dolle, III is a distinguished inventor whose work on bradykinin B1 receptor antagonists has the potential to impact the treatment of various medical conditions. His contributions to the pharmaceutical industry reflect his commitment to advancing healthcare through innovative solutions.