The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 19, 2005

Filed:

Jan. 14, 2002
Applicants:

Michael H. J. Ohlmeyer, Plainsboro, NJ (US);

John J. Baldwin, Gwynedd Valley, PA (US);

Roland E. Dolle, Iii, King of Prussia, PA (US);

Vidyadhar Paradkar, Somerville, NJ (US);

Jorge Gabriel Quintero, Sayreville, NJ (US);

Gonghua Pan, Groton, CT (US);

Inventors:

Michael H. J. Ohlmeyer, Plainsboro, NJ (US);

John J. Baldwin, Gwynedd Valley, PA (US);

Roland E. Dolle, III, King of Prussia, PA (US);

Vidyadhar Paradkar, Somerville, NJ (US);

Jorge Gabriel Quintero, Sayreville, NJ (US);

Gonghua Pan, Groton, CT (US);

Assignee:

Pharmacopeia Drug Discovery, Inc., Princeton, NJ (US);

Attorneys:
Int. Cl.
CPC ...
C07D403/04 ; C07D409/04 ; C07D417/04 ; A61K031/506 ; A61P003/10 ;
U.S. Cl.
CPC ...
Abstract

Bradykinin B-receptor antagonists of formulaare disclosed. The compounds are useful for treating diseases associated with inappropriate bradykinin receptor activity, such as diabetic vasculopathy, inflammation, pain, hyperalgesia, asthma, rhinitis, septic shock, atherosclerosis and multiple sclerosis. Pyrimidines, triazines, and anilines in which Q is imidazolyl or pyrrolyl are particularly preferred.


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