Company Filing History:
5 out of 22 
1 out of 1,248 
1 out of 637 
Years Active: 1997-2011
Title: Rogier Maria Bertina: Innovator in Genetic Screening
Introduction
Rogier Maria Bertina is a prominent inventor based in Leiden, Netherlands. He has made significant contributions to the field of genetics, particularly in the area of screening for genetic defects associated with thrombosis. With a total of seven patents to his name, Bertina's work has had a substantial impact on medical research and diagnostics.
Latest Patents
Among his latest patents is a method for screening for the presence of a genetic defect associated with deep venous thrombosis. This invention relates to identifying a genetic marker in an individual's genome that indicates an increased risk of this condition. The genetic marker is haplotype 2 of the fibrinogen γ gene (FGG-H2), which includes a set of mutations in the nucleic acid material encoding fibrinogen γ. The specific mutations are selected from a group that includes 129A/T, 7874G/A, 9615'C/T, and 10034C/T.
Another notable patent involves a method for screening for the presence of a genetic defect associated with thrombosis and/or poor anticoagulant response to activated protein C. This method focuses on detecting mutations at the cleavage and/or binding sites for activated protein C of Factor V and/or Factor Va, as well as Factor VIII and/or Factor VIIIa, at either the nucleic acid or protein level.
Career Highlights
Bertina has worked at Rijksuniversiteit Leiden, where he has contributed to various research projects and advancements in genetic screening. His expertise in the field has led to the development of innovative methods that enhance the understanding of genetic predispositions to thrombosis.
Collaborations
Throughout his career, Bertina has collaborated with notable colleagues, including Pieter Hendrik Reitsma and Bonno Nammen Bouma. These partnerships have fostered a collaborative environment that has propelled advancements in genetic research.
Conclusion
Rogier Maria Bertina's contributions to genetic screening have paved the way for improved diagnostic methods in thrombosis. His innovative patents and collaborative efforts continue to influence the field of genetics and enhance patient care.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.