The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 29, 2011
Filed:
Mar. 31, 2006
Rogier Maria Bertina, Leiden, NL;
Frits R. Rosendaal, Wassenaar, NL;
Shirley Uitte DE Willige, Leeds, GB;
Maria Catharina Henrica DE Visser-van Soest, Leiderdorp, NL;
Hans Luuk Vos, Bodegraven, NL;
Rogier Maria Bertina, Leiden, NL;
Frits R. Rosendaal, Wassenaar, NL;
Shirley Uitte de Willige, Leeds, GB;
Maria Catharina Henrica de Visser-van Soest, Leiderdorp, NL;
Hans Luuk Vos, Bodegraven, NL;
Biomerieux B.V., RM Boxtel, NL;
Abstract
The present invention relates to a method for screening an individual for the presence in his/her genome of a genetic marker that is indicative of an increased risk of deep venous thrombosis, wherein the genetic marker is haplotype 2 of the fibrinogen γ gene (FGG-H2) as given in FIG.A. The genetic marker comprises a set of one, two, three or four mutations in the nucleic acid material encoding fibrinogen γ, the mutations being selected from the group consisting of 129A/T (rs2066854), 7874G/A (rs20668β1), 9615'C/T (rs2066864) and 10034C/T (rs2066865).