The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 23, 1999
Filed:
Feb. 21, 1997
Applicant:
Inventors:
Rogier Maria Bertina, Leiden, NL;
Pieter Hendrik Reitsma, Leiden, NL;
Assignee:
Rijks Universiteit Leiden, Leiden, NL;
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12P / ; G01N / ; C12Q / ; C07K / ;
U.S. Cl.
CPC ...
435 696 ; 435-72 ; 435-792 ; 435-794 ; 435-6 ; 53038825 ; 53038885 ; 5303879 ; 530381 ;
Abstract
Method for screening for the presence of a genetic defect associated with thrombosis and/or poor anticoagulant response to activated protein C (APC). The method is directed at detecting one or more mutations at one or more of the cleavage and/or binding sites for APC of Factor V and/or Factor Va or at Factor VIII and/or Factor VIIIa at either nucleic acid or protein level or both.