Location History:
- Philadelphia, PA (US) (2001)
- Chalfont, PA (US) (1996 - 2010)
Company Filing History:
8 out of 528 
1 out of 81 
1 out of 832,843 Years Active: 1996-2010
Title: Innovations and Contributions of Roger J Pomerantz
Introduction
Roger J Pomerantz is a notable inventor based in Chalfont, PA (US), recognized for his significant contributions to the field of retroviral infection treatment. With a total of 10 patents to his name, Pomerantz has made strides in developing therapeutic targets and methods that address critical challenges in HIV-1 replication.
Latest Patents
Among his latest patents, one focuses on cellular targets for the treatment of retroviral infection. This patent discloses cellular targets comprising ATR kinase and its relevant substrates, which are essential for the final step of retroviral DNA integration. The patent also includes assays for identifying modulators of retroviral integration via the ATR kinase pathway, along with pharmaceutical preparations and methods for treating retroviral infections. Another significant patent involves the multimerization of the HIV-1 Vif protein as a therapeutic target. This patent describes a method for screening antagonists of Vif by contacting its multimerization domain with test compounds that specifically bind to it. The identified antagonists inhibit Vif multimerization, thereby disrupting essential functions of Vif and serving as potential inhibitors of HIV-1 replication.
Career Highlights
Pomerantz has had a distinguished career, working at Thomas Jefferson University, where he has contributed to various research initiatives. His work has focused on understanding the mechanisms of retroviral infections and developing innovative therapeutic strategies.
Collaborations
Throughout his career, Pomerantz has collaborated with notable colleagues, including Hui Zhang and Bin Yang, enhancing the impact of his research through teamwork and shared expertise.
Conclusion
Roger J Pomerantz's innovative work in the field of retroviral infection treatment exemplifies the importance of research and development in combating viral diseases. His patents and contributions continue to pave the way for advancements in therapeutic approaches.