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1 out of 1 Years Active: 1998-2002
Title: Roger G Clerc: Innovator in Transcriptional Regulation
Introduction
Roger G Clerc is a notable inventor based in Binningen, Switzerland. He has made significant contributions to the field of molecular biology, particularly in the area of transcriptional regulation. With a total of 3 patents, his work has had a profound impact on our understanding of gene expression.
Latest Patents
Clerc's latest patents focus on nuclear factors associated with transcriptional regulation. He describes constitutive and tissue-specific protein factors that bind to transcriptional regulatory elements of immunoglobulin (Ig) genes, including both promoters and enhancers. These factors were identified and isolated through an improved assay for protein-DNA binding. His research highlights the potential to isolate genes encoding factors that positively regulate transcription, which can be employed to enhance the transcription of Ig genes. Notably, his work includes the gene encoding NF-kB, as well as IkB and its associated uses.
Career Highlights
Throughout his career, Roger G Clerc has worked with prestigious institutions such as the Massachusetts Institute of Technology and Harvard College. His research has contributed to advancements in the understanding of transcriptional mechanisms and their implications in various biological processes.
Collaborations
Clerc has collaborated with esteemed colleagues, including David Baltimore and Ranjan Sen. These partnerships have further enriched his research and expanded the impact of his findings in the scientific community.
Conclusion
Roger G Clerc's innovative work in transcriptional regulation has led to significant advancements in molecular biology. His patents and collaborations reflect his dedication to enhancing our understanding of gene expression and its regulatory mechanisms.