Rocco Casagrande

Title: Rocco Casagrande: Innovator in Cell Immobilization Technology

Introduction

Rocco Casagrande is a notable inventor based in Newton, MA, who has made significant contributions to the field of cell immobilization technology. With a total of three patents to his name, he has developed innovative devices that enhance the capabilities of biological research and applications.

Latest Patents

One of Rocco's latest patents is a "Device for Magnetic Immobilization of Cells." This invention relates to an apparatus and methods that immobilize one or more cells associated with magnetic material on a substrate featuring one or more magnetic receptacles. The size of these receptacles determines the number of target cells that can be immobilized, which is influenced by the strength of a localized magnetic field gradient. This gradient can be generated by either permanent magnets embedded in the substrate or an external magnet focused by highly-permeable magnetic materials. The apparatus includes a removable cell delivery device and a substrate with magnetic receptacles.

Another significant patent is the "Cell Isolation and Screening Device and Method of Using Same." This invention provides methods and devices for screening a single cell or a small group of cells for desired biological activity. It allows for the delivery of cells to various isolation regions, transferring them to wells for expansion, and detecting their potential biological activities. Each receptacle is designed to isolate a single cell or small group, while the wells provide sufficient volume for cell proliferation.

Career Highlights

Rocco Casagrande is currently associated with Surface Logix, Inc., where he continues to innovate in the field of cell technology. His work has been instrumental in advancing methods for cell manipulation and analysis, which are crucial for various biological and medical applications.

Collaborations

Rocco collaborates with talented individuals such as Evelyn Wang and Enoch Kim, who contribute to the innovative environment at Surface Logix, Inc. Their combined expertise fosters a dynamic approach to research and development in cell technology.

Conclusion

Rocco Casagrande's contributions to cell immobilization technology through his patents and work at Surface Logix, Inc. highlight his role as a significant innovator in the field. His inventions are paving the way for advancements in biological research and applications.