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For the Inventor, By the Inventor

San Diego, CA, United States of America

Roberto Mariani

This inventor holds 17 USPTO granted patents and 6 published patent applications and 3 EPO patents, primarily in Biotechnology. Top assignees: Ambrx, Inc., Calder Biosciences Inc., The United States of America, as Represented by the Secretary, Department of Health and Human Services. Active years: 2009-2026.

IDiyas Innovation Intelligence. (2026). Inventor Profile: Roberto Mariani. Retrieved from https://idiyas.com/inventor/roberto-mariani

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

Calculating rank
USPTO Granted Patents = 17 

% Patents Active = 88.2

 

Average Co-Inventor Count = 6.3

ph-index = 8

Forward Citations = 258(Granted Patents)


Location History:

  • Ferentino, IT (2020 - 2021)
  • San Diego, CA (US) (2009 - 2024)
  • New York, NY (US) (2022 - 2024)

Company Filing History:

goldMedal10 out of 117 
 
Ambrx, Inc.
 patents
silverMedal2 out of 5 
 
Calder Biosciences Inc.
 patents
bronzeMedal1 out of 3,699 
 
The United States of America, as Represented by the Secretary, Department of Health and Human Services
 patents
4. 3 out of 834,601 
Other
 patents
where one patent can have more than one assignee

Years Active: 2009-2026

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Areas of Expertise:
RSV Proteins
FGF-21 Polypeptides
Biosynthetic Polypeptides
Nucleic Acids
Amino Acids
Pegylated Interferon
Methods of Treatment
Modified Polypeptides
Conformational Stability
17 patents (USPTO):Explore Patents
1. 12703721 - CONFORMATIONALLY STABILIZED RSV PRE-FUSION F PROTEINS (2026-08-11),
2. 11993637 - Modified FGF-21 polypeptides with non-naturally encoded amino acids (2024-05-28),
3. 11993633 - Conformationally stabilized RSV pre-fusion F proteins (2024-05-28),
4. 11926649 - Conformationally stabilized RSV pre-fusion F proteins (2024-03-12),
5. 11267848 - Conformationally stabilized RSV pre-fusion F proteins (2022-03-08),
6. 11103099 - Beverage dispensing machine (2021-08-31),
7. 10961291 - Modified FGF-21 polypeptides and their uses (2021-03-30),
8. 10772462 - Heating device (2020-09-15),
9. 10377805 - Modified FGF-21 polypeptides comprising non-naturally encoding amino acids and their uses (2019-08-13),
10. 10125172 - Conformationally stabilized RSV pre-fusion F proteins (2018-11-13),
11. 9975936 - Nucleic acids encoding modified FGF-21 polypeptides comprising non-naturally occurring amino acids (2018-05-22),
12. 9517273 - Methods of treatment using modified FGF-21 polypeptides comprising non-naturally occurring amino acids (2016-12-13),
13. 9079971 - Modified FGF-21 polypeptides comprising non-naturally occurring amino acids (2015-07-14),
14. 8383365 - Methods of making FGF-21 mutants comprising non-naturally encoded phenylalanine derivatives (2013-02-26),
15. 8093356 - Pegylated human interferon polypeptides (2012-01-10),

Title: The Innovative Contributions of Roberto Mariani

Introduction

Roberto Mariani is a prominent inventor based in San Diego, CA, known for his significant contributions to the field of biotechnology. With a total of 17 patents to his name, Mariani has made remarkable advancements, particularly in the development of proteins and polypeptides that have potential applications in medical treatments and vaccines.

Latest Patents

Among his latest innovations, Mariani has developed conformationally stabilized respiratory syncytial virus (RSV) pre-fusion F proteins. This invention includes RSV F proteins, polypeptides, and protein complexes that feature cross-links to stabilize them in their pre-fusion conformation. Additionally, he has introduced modified FGF-21 polypeptides that incorporate non-naturally encoded amino acids, expanding the potential uses of these proteins in therapeutic applications.

Career Highlights

Throughout his career, Mariani has worked with various companies, including Ambrx, Inc., where he has contributed to groundbreaking research and development projects. His work has not only advanced scientific understanding but has also paved the way for new treatment options in the medical field.

Collaborations

Mariani has collaborated with notable professionals in his field, including Nick Knudsen and Vadim Kraynov. These partnerships have fostered innovation and have been instrumental in the successful development of his patented technologies.

Conclusion

Roberto Mariani's contributions to biotechnology through his patents and collaborations highlight his role as a leading inventor in the industry. His work continues to influence the development of new medical therapies and vaccines, showcasing the importance of innovation in improving health outcomes.

Profile summary based on public USPTO records.
Data Sources: USPTO Patent Grant XML, Patent Center, EPO & CIPO • Normalized by IDiyas Innovation Graph. Methodology & provenance architecturePlease report any incorrect information to [email protected]
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