Company Filing History:
Years Active: 2005
Title: The Innovative Contributions of Roberto Malinow
Introduction
Roberto Malinow is a prominent inventor based in Cold Spring, NY (US). He has made significant contributions to the field of neuroscience, particularly in the area of Alzheimer's disease research. His innovative work has led to the development of diagnostic methods that can aid in drug screening for this debilitating condition.
Latest Patents
Roberto Malinow holds a patent for "Diagnostic methods for drug screening for Alzheimer's disease." This patent outlines methods of screening candidate drugs for the treatment of Alzheimer's disease. By utilizing tissue slices of mutant mouse hippocampal cells that possess an extra copy of a mutant form of the presenilin-1 gene, it has been discovered that these cells exhibit enhanced potentiation to tetanic stimuli. The method involves subjecting both wild-type and mutant hippocampal cells to tetanic stimuli in the presence of a candidate drug. A successful candidate drug is indicated by a reduction in the enhanced potentiation of the mutant cells without significant changes in the potentiation of the wild-type cells.
Career Highlights
Roberto Malinow is affiliated with Cold Spring Harbor Laboratory, where he conducts his research. His work has been instrumental in advancing our understanding of the mechanisms underlying Alzheimer's disease and the potential therapeutic approaches to combat it.
Collaborations
Some of his notable coworkers include Shahid Zaman and Sangram S Sisodia. Their collaborative efforts contribute to the ongoing research and development of innovative solutions in the field of neuroscience.
Conclusion
Roberto Malinow's contributions to Alzheimer's disease research through his patented diagnostic methods exemplify the importance of innovation in addressing complex medical challenges. His work continues to inspire advancements in the field and offers hope for future treatments.