Location History:
- Singapore, SG (2012 - 2016)
- Immunos, SG (2016)
Company Filing History:
2 out of 24 
1 out of 1,476 
1 out of 832,812 Years Active: 2012-2016
Title: The Innovations of Robert Zweigerdt
Introduction
Robert Zweigerdt is a notable inventor based in Singapore, known for his significant contributions to the field of stem cell research. He holds a total of four patents that focus on the differentiation of pluripotent stem cells, particularly in the development of cardiomyocytes and neural progenitors. His work has implications for regenerative medicine and therapeutic applications.
Latest Patents
Zweigerdt's latest patents include a process for differentiating stem cells, specifically human embryonic stem (hES) cells, into cardiomyocytes and neural progenitors. This invention provides a method that utilizes a defined medium free of xeno- and serum-components, ensuring clinical compliance. The defined media contains specific factors that promote differentiation into cardiomyocytes and neural progenitors. Another significant patent relates to the direct differentiation of cardiomyocytes from hES cells, highlighting the role of factors such as prostaglandin I2 (PGI2), Fgf 9, Bmp6, Bmp4, Scf, Igf2, and insulin in this process. This patent also includes media formulations suitable for inducing cardiomyocyte differentiation and identifies genes that are upregulated during this process.
Career Highlights
Throughout his career, Robert Zweigerdt has worked with Es Cell International Pte Ltd, where he has made substantial contributions to stem cell technology. His expertise in this area has positioned him as a key figure in advancing the understanding and application of stem cell differentiation.
Collaborations
Zweigerdt has collaborated with notable professionals in the field, including Bruce Paul Davidson and Xiuqin Xu. These collaborations have further enriched his research and innovations in stem cell differentiation.
Conclusion
Robert Zweigerdt's work in stem cell research and his innovative patents have made a significant impact on the field. His contributions continue to pave the way for advancements in regenerative medicine and therapeutic applications.