Durham, NC, United States of America

Robert R Salzler

USPTO Granted Patents = 5 

 

Average Co-Inventor Count = 2.0

ph-index = 2

Forward Citations = 24(Granted Patents)


Location History:

  • Durham, NC (US) (2012 - 2015)
  • Tarrytown, NY (US) (2023)

Company Filing History:


Years Active: 2012-2024

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5 patents (USPTO):Explore Patents

Title: Innovations of Robert R Salzler

Introduction

Robert R Salzler is a notable inventor based in Durham, NC (US), recognized for his contributions to the field of biotechnology. He holds a total of five patents, showcasing his innovative approach to solving complex problems in medical science.

Latest Patents

Salzler's latest patents focus on systems and methods for identifying HLA-associated tumor peptides. These patents detail processes for determining amino acid sequences of peptides that bind to MHC-I or HLA-I complex or MHC-II or HLA-II complex. One embodiment of his work involves isolating peptides from MHC or HLA class I or class II-peptide complexes. The method includes adding known labeled peptides of interest to create a sample containing both labeled and unlabeled isolated peptides. The analysis of this sample is conducted using an LC-MS/MS system to obtain sequence data of the peptides. Furthermore, the method enhances the sensitivity of the LC-MS/MS system when a labeled peptide is detected. Ultimately, it concludes with determining the amino acid sequence of the unlabeled peptides within a specific m/z range that includes the m/z of the labeled peptide. The system can be programmed to increase sensitivity in proximity to the m/z of the labeled peptide through an algorithm or computer program.

Career Highlights

Robert R Salzler is currently employed at Regeneron Pharmaceuticals, Inc., where he continues to advance his research and development efforts. His work has significantly impacted the understanding of peptide interactions in the context of immunology and cancer research.

Collaborations

Salzler collaborates with esteemed colleagues, including Lynn Macdonald and Andrew J Murphy, contributing to a dynamic research environment that fosters innovation and discovery.

Conclusion

Robert R Salzler's innovative work in identifying HLA-associated tumor peptides exemplifies the intersection of technology and medicine. His contributions continue to pave the way for advancements in therapeutic strategies and patient care.

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