The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 23, 2013

Filed:

Dec. 14, 2011
Applicants:

Lynn Macdonald, White Plains, NY (US);

Andrew J. Murphy, Croton-on-Hudson, NY (US);

Nicholas J. Papadopoulos, LaGrangeville, NY (US);

Marc R. Morra, Beacon Falls, CT (US);

Robert R. Salzler, Durham, NC (US);

Michael L. Lacroix-fralish, Sleepy Hollow, NY (US);

Inventors:

Lynn MacDonald, White Plains, NY (US);

Andrew J. Murphy, Croton-on-Hudson, NY (US);

Nicholas J. Papadopoulos, LaGrangeville, NY (US);

Marc R. Morra, Beacon Falls, CT (US);

Robert R. Salzler, Durham, NC (US);

Michael L. LaCroix-Fralish, Sleepy Hollow, NY (US);

Assignee:

Regeneron Pharmaceuticals, Inc., Tarrytown, NY (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); A61K 39/395 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention provides methods for treating pruritus by blocking human protease activated receptor-2 (PAR2) activity. The methods of the invention can be used to treat pruritus associated with atopic dermatitis, psoriasis, burn scarring, hypertrophic scarring, keloids, renal failure or hepatic failure. The methods of the invention include administering an antibody or antigen-binding fragment thereof that specifically binds human PAR2.


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