Company Filing History:
8 out of 4,124 
3 out of 126 
1 out of 6,850 
Years Active: 1996-2006
Title: The Innovative Contributions of Robert M Goodman
Introduction
Robert M Goodman is a notable inventor based in Madison, WI (US), recognized for his significant contributions to the field of biotechnology. With a total of 13 patents to his name, Goodman has made strides in developing novel compounds with potential therapeutic applications.
Latest Patents
Goodman's latest patents include groundbreaking work on triaryl cation antibiotics derived from environmental DNA. This invention discloses triaryl cationic compounds that exhibit broad-spectrum antibiotic and antifungal activity. The pharmaceutical compositions containing these compounds offer methods for treating bacterial and fungal infections. The compounds were initially isolated by screening a 25,000-member bacterial artificial chromosome (BAC) library of environmental DNA from soil. Notably, one clone produced a dark brown melanin-like compound that demonstrated antibiotic activity. The compounds were isolated and synthesized de novo, revealing a single open reading frame that shares extensive sequence similarity with members of the 4-hydroxyphenylpyruvate family of enzymes, which is essential for the production of these compounds. Additionally, Goodman has developed methods and compositions for accessing a diverse genetic pool for genes involved in biosynthetic pathways, further enhancing the potential for discovering new compounds.
Career Highlights
Throughout his career, Goodman has worked with prominent organizations, including the Wisconsin Alumni Research Foundation and Novartis Finance Corporation. His work has significantly impacted the field of biotechnology, particularly in antibiotic development and microbial genomics.
Collaborations
Goodman has collaborated with esteemed colleagues such as John A Ryals and Danny C Alexander, contributing to the advancement of research in his field.
Conclusion
Robert M Goodman stands out as an influential inventor whose work in biotechnology continues to pave the way for innovative solutions in medicine. His contributions, particularly in antibiotic development, highlight the importance of research and collaboration in addressing global health challenges.