Company Filing History:
2 out of 5 
2 out of 2 
1 out of 1 Years Active: 1998-2007
Title: The Innovative Contributions of Robert J Crawford
Introduction
Robert J Crawford is a prominent inventor based in West Lake Shores, Australia, recognized for his significant contributions to the field of xenotransplantation. With a total of three patents to his name, Crawford’s work has advanced the understanding and management of hyperacute rejection responses in transplantation procedures.
Latest Patents
Crawford's latest patents focus on the development of materials and methods for managing hyperacute rejection in human xenotransplantation. His innovative approach addresses the role of human pre-formed xenoantibodies in hyperacute rejection. His patent describes methods for effectively removing or neutralizing such antibodies from the human recipient. Furthermore, it includes strategies for reducing or eliminating specific epitopes in donor organs, which these antibodies recognize. These epitopes are produced by the enzyme α-1,3 galactosyltransferase, a target in his research. The patent also details the porcine gene encoding the α-1,3 galactosyltransferase and outlines methods for inactivating this gene in mammalian cells and embryos. Moreover, Crawford introduces a novel leukemia inhibitory factor (T-LIF) that aids in the maintenance of embryonic stem cells and primordial germ cells in culture.
Career Highlights
Throughout his career, Robert J Crawford has worked with reputable organizations such as Bresagen, Inc. and St. Vincent's Hospital. His experience in these institutions has allowed him to spearhead innovative research and practical applications in the medical field, particularly in the realm of transplantation biology.
Collaborations
Crawford has collaborated with notable colleagues, including Martin J Pearse and Allan J Robins. Their collective efforts have contributed to the advancement of knowledge and techniques in xenotransplantation, paving the way for potential breakthroughs in medical treatments.
Conclusion
Robert J Crawford’s pioneering work in the field of xenotransplantation exemplifies the impact of innovative research on medical science. His patents and collaborations highlight his commitment to overcoming challenges in transplantation, ultimately improving patient outcomes. As advancements continue in this area, Crawford’s contributions will remain integral to the evolution of medical practices surrounding organ transplants.