Annandale, NJ, United States of America

Robert F Rando


Average Co-Inventor Count = 3.7

ph-index = 7

Forward Citations = 133(Granted Patents)


Location History:

  • The Woodlands, TX (US) (1995 - 2002)
  • Beaconsfield, CA (2001 - 2005)
  • Annandale, NJ (US) (2003 - 2011)

Company Filing History:


Years Active: 1995-2011

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16 patents (USPTO):Explore Patents

Title: The Innovative Achievements of Robert F. Rando: A Pioneer in RNA Research

Introduction: Robert F. Rando, an esteemed inventor based in Annandale, NJ, has made significant contributions to the fields of molecular biology and pharmacology. With a remarkable portfolio that includes 16 patents, Rando has been pivotal in advancing methods for identifying compounds with therapeutic potential.

Latest Patents: Among Rando's notable patents is a groundbreaking invention concerning methods for identifying small molecules that modulate premature translation termination and nonsense-mediated mRNA decay. This innovative method involves screening and identifying compounds that interact with target ribonucleic acid (RNA), particularly focusing on binding sites in the 28S ribosomal RNA. The invention offers a simple yet sensitive assay designed for high-throughput screening of compound libraries, ultimately aiming to discover pharmaceutical leads.

Another significant patent by Rando details the development of oligonucleotide inhibitors of bcl-xL. This invention encompasses antisense oligonucleotides that target specific nucleotide sequences to treat cancer by reducing the levels of bcl-xL protein in tumor cells. The methodologies include utilizing delivery agents such as porphyrin or lipofectin, showcasing Rando's innovative approach to cancer therapeutics.

Career Highlights: Rando's professional journey includes valuable experiences at prominent companies, such as Aronex Pharmaceuticals, Inc. and Biochem Pharma Inc. He has played a crucial role in research and development efforts aimed at enhancing drug efficacy and targeting mechanisms.

Collaborations: Throughout his career, Robert F. Rando has collaborated with esteemed colleagues, including Michael E. Hogan and Susan Fennewald. These partnerships have undoubtedly contributed to the success and impact of his inventions, fostering a collaborative environment that encourages innovation.

Conclusion: Robert F. Rando's impressive record of innovation and his dedication to advancing scientific knowledge have positioned him as a noteworthy figure in the realm of RNA research and drug development. His patents not only enhance our understanding of molecular biology but also hold the potential to lead to novel cancer treatments. Through his remarkable contributions, Rando continues to inspire future generations of inventors and researchers.

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