The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 22, 1997

Filed:

Jun. 06, 1994
Applicant:
Inventors:

Bharat B Aggarwal, Houston, TX (US);

Robert F Rando, The Woodlands, TX (US);

Michael E Hogan, The Woodlands, TX (US);

Assignee:

Research Development Foundation, Carson City, NV (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N / ; C07H / ; C12Q / ; G01N / ;
U.S. Cl.
CPC ...
435375 ; 435-6 ; 435-723 ; 514 44 ; 536 245 ; 536 2431 ; 536 2432 ; 536 2433 ;
Abstract

The present invention provides novel methods of treating anti-neoplastic and non-neoplastic cell proliferative diseases. The present methods involve administration of triplex forming oligonucleotides to humans to inhibit the biological activity of tumor necrosis factor. Also provided are methods of treating neuro-oncologic states and renal cancer.


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