Company Filing History:
Years Active: 2019-2025
Title: Innovations of Robert F. Pagels
Introduction
Robert F. Pagels is a notable inventor based in Princeton, NJ, with a significant contribution to the field of nanoparticle technology. He holds a total of six patents, showcasing his innovative approach to solving complex challenges in medical applications.
Latest Patents
Among his latest patents is the development of triblock copolymer stabilizers for the formation of nanoparticles encapsulating soluble biologics, therapeutics, and imaging agents. This invention addresses the challenges faced by hydrophilic molecules, such as biologics, which include peptides and proteins, in terms of poor membrane permeability and rapid clearance from the bloodstream. The patent outlines methods for creating a core-shell-brush nanoparticle using an A-B-C triblock copolymer, where the hydrophilic core contains the biologic, and the shell is formed from the precipitated B Block. The A Block serves as a stabilizing brush layer, allowing for the assembly of particles through sequential precipitations under defined mixing conditions. Additionally, he has patented methods for forming cellulosic polymer nanoparticles that incorporate a hydrophobic material, further advancing the field of nanoparticle technology.
Career Highlights
Robert F. Pagels has made significant strides in his career, particularly through his work at Princeton University. His research focuses on the intersection of polymer science and biomedical applications, leading to innovative solutions that enhance the delivery and efficacy of therapeutic agents.
Collaborations
He has collaborated with esteemed colleagues, including Robert K. Prud'homme and Chester E. Markwalter, contributing to a rich environment of innovation and research.
Conclusion
Robert F. Pagels exemplifies the spirit of innovation in the field of nanoparticle technology, with his patents paving the way for advancements in medical applications. His work continues to influence the development of effective therapeutic solutions.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.