The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 31, 2021
Filed:
Dec. 21, 2016
Applicant:
The Trustees of Princeton University, Princeton, NJ (US);
Inventors:
Robert K. Prud'Homme, Princeton, NJ (US);
Robert F. Pagels, Princeton, NJ (US);
Chester E. Markwalter, Princeton, NJ (US);
Assignee:
THE TRUSTEES OF PRINCETON UNIVERSITY, Princeton, NJ (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/50 (2006.01); B01J 13/06 (2006.01); A61K 9/16 (2006.01); A61K 9/51 (2006.01); A61K 9/00 (2006.01);
U.S. Cl.
CPC ...
A61K 9/5089 (2013.01); A61K 9/1647 (2013.01); A61K 9/5026 (2013.01); A61K 9/5031 (2013.01); A61K 9/5138 (2013.01); A61K 9/5146 (2013.01); A61K 9/5153 (2013.01); A61K 9/5192 (2013.01); B01J 13/06 (2013.01); A61K 9/0019 (2013.01);
Abstract
An 'inverse' precipitation route to precipitate aqueous soluble species with copolymers as nanoparticles having a hydrophilic, polar core and a less polar shell is described. The aggregation of these nanoparticles to form larger microparticles and monoliths provides a highly loaded construct (e.g., a depot) for the sustained and controlled release of actives.