Robert A Horlick

Title: The Innovations of Robert A. Horlick

Introduction

Robert A. Horlick is a notable inventor based in Plainsboro, NJ (US). He has made significant contributions to the field of biotechnology, particularly in the area of gene cloning and receptor characterization. With a total of 3 patents, his work has advanced our understanding of bradykinin receptors and their potential therapeutic applications.

Latest Patents

Horlick's latest patents include groundbreaking research on the cloning and characterization of genes encoding bradykinin B1 receptor homologues from five mammalian species. This work involves the cloning and characterization of genes for bradykinin B receptors from species such as the vervet monkey, rhesus macaque, tree shrew, dog, and pig. In addition to detailing the nucleotide and amino acid sequences, the patent describes methods for identifying modulators of bradykinin B receptor activity using these molecules. Furthermore, it provides a method for identifying an animal model useful in screening potential therapeutic agents.

Another significant patent by Horlick is a method for the maintenance and selection of episomes. This method involves transfecting a eukaryotic cell with an episome under specific conditions that allow for the survival of successfully transfected cells. The resulting cells express both a first protein that induces cell death and a second protein that prevents cell death caused by the first protein.

Career Highlights

Horlick has been associated with Pharmacopeia Inc., where he has contributed to various innovative projects. His work has not only advanced scientific knowledge but has also paved the way for potential therapeutic developments in medicine.

Collaborations

Throughout his career, Horlick has collaborated with esteemed colleagues such as Bassam B. Damaj and Alan K. Robbins. These collaborations have further enriched his research and expanded the impact of his inventions.

Conclusion

Robert A. Horlick's contributions to biotechnology through his patents and collaborations highlight his role as a significant inventor in the field. His work continues to influence research and development in therapeutic applications.