Richard Smith

Title: Richard Smith: Innovator in Antigen Binding Proteins

Introduction

Richard Smith is a notable inventor based in Mountain View, CA (US). He has made significant contributions to the field of biotechnology, particularly in the development of antigen binding proteins. With a total of 4 patents to his name, Smith's work has the potential to impact various therapeutic applications.

Latest Patents

One of Richard Smith's latest patents focuses on low-viscosity antigen binding proteins and methods of making them. This invention concerns a method for preparing antigen binding proteins specific for PCSK9 with reduced viscosity. The method involves replacing residues in high viscosity variable domain subfamilies with residues in correlating low viscosity subfamilies. Additionally, it includes substituting residues in the Fc domain with those associated with low viscosity and adding charged residues to the C-terminus of the Fc domain. The invention also encompasses antigen binding proteins produced by this method. Another significant patent involves binding proteins that specifically bind to β-Klotho or portions thereof, FGFR1c or portions thereof, or both FGFR1c and β-Klotho. This patent provides coding sequences, methods of treatment, and pharmaceutical compositions.

Career Highlights

Throughout his career, Richard Smith has worked with prominent companies in the biotechnology sector, including Amgen Inc. and Amgen Mountain View, Inc. His experience in these organizations has allowed him to refine his skills and contribute to groundbreaking innovations in the field.

Collaborations

Richard has collaborated with talented individuals such as Alice Bakker and Amy N Duguay. These partnerships have likely enhanced his research and development efforts, leading to successful innovations.

Conclusion

In summary, Richard Smith is a distinguished inventor whose work in antigen binding proteins has the potential to advance therapeutic solutions. His innovative patents and collaborations reflect his commitment to improving healthcare through biotechnology.