Richard L Wagner

Title: Richard L Wagner: Innovator in Nuclear Receptor Modulation

Introduction

Richard L Wagner is a notable inventor based in San Francisco, CA. He has made significant contributions to the field of nuclear receptor modulation, holding a total of 5 patents. His work has implications in various biological processes and therapeutic applications.

Latest Patents

One of Wagner's latest patents is focused on methods for modulating nuclear receptor coactivator binding. This invention relates to methods and agonist/antagonist compounds that can influence the binding of coactivators to nuclear receptors. The patent outlines a method for identifying residues that comprise a coactivator binding site for a nuclear receptor of interest. Additionally, it includes a method for identifying agonists and antagonists that bind to these sites. The invention is exemplified by the manipulation of the coactivator binding site of the thyroid receptor (TR) and extends to other nuclear receptors such as RAR, RXR, PPAR, VDR, ER, GR, PR, MR, and AR. Another significant patent involves a security closure for a container, which features a cap with flexible, independently movable skirt portion segments that engage with a pivoted lever for secure latching.

Career Highlights

Throughout his career, Richard L Wagner has worked with esteemed institutions, including the University of California. His innovative approaches have led to advancements in the understanding and application of nuclear receptor biology.

Collaborations

Wagner has collaborated with notable individuals in his field, including John D Baxter and Robert J Fletterick. Their combined expertise has contributed to the success of his research and inventions.

Conclusion

Richard L Wagner's contributions to the field of nuclear receptor modulation highlight his innovative spirit and dedication to advancing scientific knowledge. His patents reflect a commitment to developing methods that can have a lasting impact on therapeutic strategies.