Company Filing History:
Years Active: 2009-2021
Title: Richard Hercek: Innovator in Pharmaceutical Chemistry
Introduction
Richard Hercek is a notable inventor based in Hlohovec, Slovakia. He has made significant contributions to the field of pharmaceutical chemistry, particularly in the development of methods for the purification and preparation of important pharmaceutical compounds. With a total of 2 patents, his work has the potential to impact the pharmaceutical industry positively.
Latest Patents
Hercek's latest patents include a method for the isolation and purification of naltrexone. This invention describes a process for purifying naltrexone base from reaction mixtures concentrated by evaporation and/or from mixtures containing naltrexone in the presence of other organic or inorganic substances. The method utilizes trituration and/or extraction and crystallization from cyclopentyl methyl ether (CPME), optionally from a mixture of CPME and another organic solvent. The result is high-purity naltrexone, which can be used in a parenteral dosage form.
Another significant patent is the process for the preparation of carvedilol. This invention outlines a new method for synthesizing carvedilol for pharmaceutical use. The synthesis involves a reaction of 4-(oxirane-2-ylmethoxy)-9H-arbazole with 2-(2-methoxyphenoxy)ethylamine salts in the presence of a base, using an alcohol solvent with 2 to 5 carbon atoms at elevated temperatures. After processing the crude reaction mixture, crude carvedilol is obtained, which is then purified by crystallization from ethyl acetate with the addition of activated carbon.
Career Highlights
Throughout his career, Richard Hercek has worked with reputable companies in the pharmaceutical sector, including Saneca Pharmaceuticals and Zentiva. His experience in these organizations has contributed to his expertise in pharmaceutical innovations.
Collaborations
Hercek has collaborated with notable professionals in his field, including Miroslav Kavala and Dusan Vandák. These collaborations have likely enriched his research and development efforts.
Conclusion
Richard Hercek's contributions to pharmaceutical chemistry through his innovative patents demonstrate his commitment to advancing medical science. His work in the purification and preparation of essential pharmaceutical compounds is noteworthy and has the potential to benefit the industry significantly.