The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 02, 2021
Filed:
Oct. 06, 2017
Saneca Pharmaceuticals A.s., Hlohovec, SK;
Miroslav Kavala, Leopoldov, SK;
Du{hacek over (s)}an Vandák, Modra, SK;
Miroslav Palík, Bratislava, SK;
Ján Ga{hacek over (s)}par, Bratislava-Dúbravka, SK;
Richard Hercek, Hlohovec, SK;
SANECA PHARMACEUTICALS A.S., Hlohovec, SK;
Abstract
The invention describes a method for purification of naltrexone base from reaction mixtures concentrated by evaporation and/or from mixtures containing naltrexone in the presence of other organic or inorganic substances by trituration and/or extraction and crystallization from cyclopentyl methyl ether (CPME), optionally from a mixture of cyclopentyl methyl ether and another organic solvent. Naltrexone of high purity is obtained by this method and can be used in a parenteral dosage form.