Richard H Kimura

Title: Richard H Kimura: Innovator in Peptide Engineering

Introduction

Richard H Kimura is a prominent inventor based in Menlo Park, CA. He has made significant contributions to the field of peptide engineering, holding a total of 6 patents. His work focuses on developing engineered peptides that have high affinity for cell surface receptors, which are crucial for various biomedical applications.

Latest Patents

Kimura's latest patents include innovative compositions and methods involving engineered peptides. These peptides are designed to bind with high affinity to the cell surface receptors of fibronectin and vitronectin. The peptides are based on a molecular scaffold that incorporates a subsequence containing the RGD integrin-binding motif. This subsequence consists of approximately 9-13 amino acids, and its sequence is determined through sequential rounds of selection, also known as in vitro evolution. The molecular scaffold is preferably based on a knottin, such as EETI, AgRP, and Agatoxin IVB, which provide a rigid three-dimensional conformation. His research demonstrates that EETI can tolerate mutations in other loops, indicating the potential use of these peptides as imaging agents.

Career Highlights

Throughout his career, Richard H Kimura has worked with notable institutions, including Leland Stanford Junior University and Sanofi. His expertise in peptide engineering has positioned him as a key figure in the development of innovative biomedical solutions.

Collaborations

Kimura has collaborated with esteemed colleagues, including Jennifer R Cochran and Aron M Levin. These partnerships have further enhanced his research and contributions to the field.

Conclusion

Richard H Kimura's work in peptide engineering exemplifies innovation in the biomedical field. His patents and collaborations reflect a commitment to advancing scientific knowledge and improving medical imaging techniques.