Richard C Egen

Title: Richard C Egen: Innovator in Meningococcal Polysaccharide Fermentation

Introduction

Richard C Egen is a notable inventor based in Cheyney, PA (US). He has made significant contributions to the field of meningococcal polysaccharide fermentation, holding 2 patents that reflect his innovative work. His research focuses on developing animal component-free fermentation processes that enhance polysaccharide production.

Latest Patents

Egen's latest patents include advancements in animal component-free meningococcal polysaccharide fermentation. He has developed a fermentation media and process based on a chemically defined medium. To improve polysaccharide production, he examined fed-batch fermentation using various feed solutions and feeding strategies. A feed solution containing glucose, amino acids, and trace metal elements produces Group A polysaccharide at approximately three times the level observed with batch fermentation. This process has been successfully used to produce polysaccharides of serotypes A, C, Y, and W-135. It has been run reproducibly at the 20L scale and can be scaled to 400L or more.

Career Highlights

Throughout his career, Richard C Egen has worked with reputable organizations, including Aventis Pasteur Limited. His work has significantly impacted the field of fermentation and polysaccharide production.

Collaborations

Egen has collaborated with notable coworkers such as Lori Ann Fortin and Willie Wei Qiang Sun. Their combined expertise has contributed to the success of his innovative projects.

Conclusion

Richard C Egen's contributions to meningococcal polysaccharide fermentation demonstrate his commitment to advancing scientific research and innovation. His work continues to influence the field and pave the way for future developments.