Richard B Mailman

Title: Richard B Mailman: Innovator in Dopamine-Related Treatments

Introduction

Richard B Mailman is a prominent inventor based in Chapel Hill, NC (US). He has made significant contributions to the field of neuroscience, particularly in the treatment of dopamine-related dysfunctions. With a total of 6 patents, his work has the potential to impact various neurological conditions.

Latest Patents

Mailman's latest patents include a method of treatment for dopamine-related dysfunction. This invention utilizes full dopamine receptor agonists in an intermittent dosing protocol, incorporating essential 'off-periods' to prevent tolerance. The method involves periodically administering a full agonist with a specific half-life, ensuring therapeutic effects while managing plasma concentrations effectively. Another notable patent involves chromeno[4,3,2-de]isoquinolines as potent dopamine receptor ligands. These compounds are designed for pharmaceutical formulations aimed at treating conditions such as Parkinson's disease, schizophrenia, and attention-deficit hyperactivity disorder, among others.

Career Highlights

Throughout his career, Richard B Mailman has been associated with reputable institutions such as the Purdue Research Foundation and the University of North Carolina at Chapel Hill. His work has garnered attention for its innovative approaches to treating complex neurological disorders.

Collaborations

Mailman has collaborated with notable figures in the field, including David E Nichols and Russell A Grubbs. These partnerships have contributed to the advancement of research and development in dopamine-related therapies.

Conclusion

Richard B Mailman stands out as a key inventor in the realm of dopamine-related treatments. His innovative patents and collaborations reflect his commitment to improving the lives of individuals affected by neurological disorders.