The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 12, 2005

Filed:

Jul. 02, 2002
Applicants:

David E. Nichols, West Lafayette, IN (US);

Russell A. Grubbs, Lafayette, IN (US);

Richard B. Mailman, Chapel Hill, NC (US);

Inventors:

David E. Nichols, West Lafayette, IN (US);

Russell A. Grubbs, Lafayette, IN (US);

Richard B. Mailman, Chapel Hill, NC (US);

Assignees:

University of North Carolina at Chapel Hill, Chapel Hill, NC (US);

Purdue Research Foundation, West Lafayette, IN (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K031/445 ;
U.S. Cl.
CPC ...
Abstract

Novel dopamine receptor ligands of the formula:pharmaceutical formulations of such compounds, and a method using such compounds for treating a patient suffering from dopamine-related dysfunction of the central or peripheral nervous system, are described. The compounds are expected to be useful in treating Parkinson's disease, improving cognition, improving memory, improving the negative symptoms of schizophrenia, improving attention-deficit hyperactivity disorder and related developmental disorders, treating substance abuse disorders, and in treating various peripheral conditions where changes in dopamine receptor occupation affects physiological function, including organ perfusion, cardiovascular function, and selected endocrine and immune system functions.


Find Patent Forward Citations

Loading…