Richard Anthony Godwin Smith

Title: The Innovations of Richard Anthony Godwin Smith

Introduction

Richard Anthony Godwin Smith is a notable inventor based in Herts, GB. He has made significant contributions to the field of organ transplantation through his innovative inventions. With a total of 6 patents, Smith has focused on developing methods and formulations that enhance the success of organ transplants.

Latest Patents

One of his latest patents is a method of preparing an organ by perfusion. This invention relates to formulations of polypeptides and their derivatives that act as inhibitors or regulators of the immune or coagulation systems, which are crucial for organ transplantation. The invention provides solutions that include complement inhibitors or regulators of T- or B-lymphocyte function in modified molecular forms. These can be used to perfuse and modify organs prior to transplantation or to store organs effectively. Additionally, it localizes agents on organs and includes a preparation for perfusion comprising a soluble derivative of a soluble polypeptide. This derivative consists of two or more heterologous membrane binding elements with low membrane affinity, which are covalently associated with the polypeptide. These elements can interact with components of membranes of the organ exposed to extracellular perfusion fluids, along with a physiologically acceptable flush storage solution.

Another significant patent involves conjugates of soluble peptidic compounds with membrane-binding agents. This invention provides soluble derivatives of soluble polypeptides that incorporate membrane binding elements. It also includes methods for making and using these soluble derivatives.

Career Highlights

Richard Anthony Godwin Smith is associated with Adprotech Limited, where he continues to work on innovative solutions in the field of organ transplantation. His expertise and inventions have contributed to advancements in medical technology.

Collaborations

Smith has collaborated with notable coworkers, including Danuta Ewa Irena Mossakowska and Ian Dodd. Their combined efforts have furthered research and development in their respective fields.

Conclusion

Richard Anthony Godwin Smith is a distinguished inventor whose work has significantly impacted organ transplantation. His innovative patents demonstrate a commitment to improving medical practices and enhancing patient outcomes.