Rhea Sumpter, Jr

Title: Rhea Sumpter, Jr.: Innovator in Viral Research

Introduction

Rhea Sumpter, Jr. is a notable inventor based in Dallas, TX (US). He has made significant contributions to the field of viral research, particularly in understanding how host cell permissiveness to viral replication can be reduced. His innovative work has implications for combating various viral infections.

Latest Patents

Rhea Sumpter, Jr. holds a patent titled "Prenylation inhibitors reduce host cell permissiveness to viral replication." This patent describes a method for reducing the permissiveness of human cells to the replication of pathogenic human viruses. The method involves treating human cells with a selective inhibitor of prenylation of a host cell protein. The targeted viruses, especially from the Flaviviridae family, are characterized by the absence of a CXXX box and a prenylated viral protein, making them reliant on host protein prenylation for replication. The process includes contacting infected human cells with an effective amount of a prenylation enzyme inhibitor and confirming a reduction in the cells' permissiveness to viral replication.

Career Highlights

Rhea Sumpter, Jr. is affiliated with The University of Texas System, where he continues to advance his research in viral replication and host interactions. His work is crucial in developing therapeutic strategies against viral infections.

Collaborations

Rhea collaborates with esteemed colleagues, including Michael S. Brown and Jin Ye, who contribute to his research endeavors. Their combined expertise enhances the impact of their work in the scientific community.

Conclusion

Rhea Sumpter, Jr. is a pioneering inventor whose research on prenylation inhibitors offers promising avenues for reducing viral replication in human cells. His contributions to the field are invaluable and continue to inspire further innovations in viral research.