This inventor holds 4 USPTO granted patents and 1 EPO patent. Top assignee: Bristol-Myers Squibb Compnay. Active years: 2009-2013.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile
Company Filing History:
Years Active: 2009-2013
Title: Innovations and Contributions of Rex Denton
Introduction
Rex Denton is a notable inventor based in Madison, CT (US), recognized for his significant contributions to the field of pharmaceuticals. With a total of four patents to his name, Denton has made strides in developing compounds that target critical receptors in the central nervous system.
Latest Patents
One of Denton's latest patents is titled "Aza-bicyclic amine N-oxide compounds as alpha-7 nicotinic acetylcholine receptor ligand pro-drugs." This invention relates to compounds that serve as prodrugs for ligands, agonists, and partial agonists for the nicotinic α7 receptor. These compounds may be beneficial in treating various disorders of the central nervous system, particularly affective and neurodegenerative disorders.
Another significant patent is the "Method of generating a dosing schedule using gamma secretase notch biomarkers." This invention focuses on the biomarker TFF-3, which measures γ-secretase mediated Notch processing. TFF-3 is useful in predicting and determining in vivo Notch-related toxicity associated with the inhibition of Notch processing mediated by γ-secretase. The methods and reagents developed can be utilized in various stages of clinical testing to identify and maintain preferred doses of test compounds, thereby preventing medical complications.
Career Highlights
Rex Denton has built a successful career at Bristol-Myers Squibb Company, where he has been instrumental in advancing pharmaceutical research and development. His work has contributed to the understanding and treatment of complex neurological disorders.
Collaborations
Denton has collaborated with esteemed colleagues, including Jere E Meredith, Jr and Kimberley A Lentz, to further enhance the impact of his research and innovations.
Conclusion
Rex Denton's innovative work in the pharmaceutical industry showcases his dedication to improving treatments for central nervous system disorders. His patents reflect a commitment to advancing medical science and enhancing patient care.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile