The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 09, 2013

Filed:

Apr. 29, 2011
Applicants:

Kimberley A. Lentz, Durham, CT (US);

Rex Denton, Madison, CT (US);

James H. Cook, Ii, East Hampton, CT (US);

Ivar M. Mcdonald, East Haddam, CT (US);

Dalton King, Hamden, CT (US);

Richard E. Olson, Orange, CT (US);

Nenghui Wang, Guilford, CT (US);

Robert A. Mate, Waterbury, CT (US);

Christiana I. Iwuagwu, Hamden, CT (US);

F. Christopher Zusi, Hamden, CT (US);

John E. Macor, Guilford, CT (US);

Matthew D. Hill, Wallingford, CT (US);

Haiquan Fang, Madison, CT (US);

Inventors:

Kimberley A. Lentz, Durham, CT (US);

Rex Denton, Madison, CT (US);

James H. Cook, II, East Hampton, CT (US);

Ivar M. McDonald, East Haddam, CT (US);

Dalton King, Hamden, CT (US);

Richard E. Olson, Orange, CT (US);

Nenghui Wang, Guilford, CT (US);

Robert A. Mate, Waterbury, CT (US);

Christiana I. Iwuagwu, Hamden, CT (US);

F. Christopher Zusi, Hamden, CT (US);

John E. Macor, Guilford, CT (US);

Matthew D. Hill, Wallingford, CT (US);

Haiquan Fang, Madison, CT (US);

Assignee:

Bristol-Myers Squibb Company, Princeton, NJ (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A01N 43/42 (2006.01); A61K 31/44 (2006.01); C07D 491/10 (2006.01); C07D 491/20 (2006.01);
U.S. Cl.
CPC ...
Abstract

The disclosure generally relates to compounds of the following formula, including their salts, as well as compositions and methods of using the compounds. The compounds are prodrugs for ligands, agonists, and partial agonists for the nicotinic α7 receptor and may be useful for the treatment of various disorders of the central nervous system, especially affective and neurodegenerative disorders.


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