Reinhard Simon

Title: Reinhard Simon: Innovator in Genetic Engineering

Introduction

Reinhard Simon is a notable inventor based in Bielefeld, Germany. He has made significant contributions to the field of genetic engineering, particularly in the development of gene transfer vectors and plasmids. With a total of 3 patents, Simon's work has advanced the understanding and application of genetic manipulation techniques.

Latest Patents

One of Simon's latest patents is a gene transfer vector that features a Tn-Mob element. This element comprises a transposon with a Mob-site inserted within it. The patent includes vectors and bacterial strains containing the Tn-Mob element, along with methods for its use, such as the production of plasmid-free bacterial strains. Another significant patent is for Class II mobilizable gram-negative plasmids. These vectors are capable of replication in a broad host range of gram-negative bacteria. They are composite plasmids that include segments derived from both an E. coli vector plasmid and a broad host range plasmid. The broad host range plasmid segment contains Mob-functions and DNA coding for replication functions, with non-essential regions deleted to enhance efficiency.

Career Highlights

Reinhard Simon is currently associated with Lubrizol Genetics, Inc., where he continues to innovate in the field of genetic engineering. His work has been instrumental in developing new methodologies for genetic manipulation, which have applications in various biotechnological fields.

Collaborations

Simon has collaborated with notable colleagues, including Alfred Puhler and Ursula Priefer. These collaborations have further enriched his research and contributed to the advancements in genetic engineering.

Conclusion

Reinhard Simon's contributions to genetic engineering through his patents and collaborations highlight his role as a leading inventor in the field. His innovative work continues to influence the landscape of genetic research and applications.