Vienna, Austria

Reingard Grabherr

USPTO Granted Patents = 4 


 

Average Co-Inventor Count = 3.0

ph-index = 1

Forward Citations = 3(Granted Patents)


Location History:

  • Pressbaum, AT (2004 - 2016)
  • Vienna, AT (2007 - 2021)

Company Filing History:


Years Active: 2004-2021

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4 patents (USPTO):Explore Patents

Title: Innovator Reingard Grabherr: Pioneering Advances in Protein Expression

Introduction

Reingard Grabherr, an accomplished inventor based in Vienna, Austria, has made significant contributions to the field of recombinant biotechnology. With a total of four patents, she has focused her research on enhancing protein expression, which is crucial for various biotechnological applications.

Latest Patents

Among her most notable patents is the invention titled "Uncoupling Growth and Protein Production." This innovative method improves the expression level of a desired protein within the production process of bacterial host cells. By expressing a phage protein that inhibits bacterial growth during production, Grabherr's method effectively minimizes the metabolic burden, oxygen demand, and metabolic heat development. This clever decoupling strategy allows the host cell to produce higher quantities of the protein of interest while avoiding stress responses associated with heterologous protein expression.

Another significant patent, "Host-Vector System Antibiotic-Free ColE1 Plasmid Propagation," introduces a host-vector system that utilizes the RNA-based copy number control mechanism of ColE1-type plasmids. This innovative system allows for antibiotic-free selection of plasmids, enhancing the production processes for plasmid DNA and recombinant proteins, thus contributing to more sustainable biotechnological practices.

Career Highlights

Throughout her career, Reingard Grabherr has worked with renowned companies in the biotechnology sector, such as Boehringer Ingelheim International GmbH and Engenes Biotech GmbH. Her work has substantially impacted advancements in protein expression techniques and bioprocess optimization.

Collaborations

Grabherr has collaborated with several esteemed professionals in her field, including Gerald Striedner and Karl Bayer. These partnerships have amplified her contributions to biotechnology and have allowed for the exchange of innovative ideas and methodologies within the industry.

Conclusion

Reingard Grabherr exemplifies the spirit of innovation through her pioneering work in biotechnology. Her advancements in protein expression methodologies not only enhance production efficiency but also pave the way for more sustainable practices in the field. As her work continues to evolve, it holds the potential to significantly impact both research and industrial biotechnology sectors.

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