Company Filing History:
Years Active: 2010
Title: Reiner Olliger: Innovator in Lipopeptide Deacylation
Introduction
Reiner Olliger is a notable inventor based in Bruchkobel, Germany. He has made significant contributions to the field of biochemistry, particularly in the enzymatic processing of lipopeptides. His innovative methods have the potential to impact various applications in pharmaceuticals and biotechnology.
Latest Patents
Olliger holds a patent for a method for the deacylation of lipopeptides. This invention relates to an enzymatic process that eliminates the N-acyl side chain from lipopeptides, forming the corresponding nucleus. The method involves preparing the lipopeptide through fermentation, where it is bound to the cells of the biomass. The biomass is then removed along with the adhering lipopeptide, resuspended in an aqueous system, and treated with a suitable deacylase. This process allows for the direct reaction of the cell-bound biomass with the deacylase, leading to the elimination of the N-acyl chain linked via an amide linkage.
Career Highlights
Reiner Olliger is associated with Sanofi-Aventis Deutschland GmbH, where he continues to develop and refine his innovative methods. His work has garnered attention for its potential applications in the pharmaceutical industry, particularly in the production of bioactive compounds.
Collaborations
Olliger has collaborated with notable colleagues such as Eberhard Ehlers and Heinrich Decker. These partnerships have contributed to the advancement of research and development in their respective fields.
Conclusion
Reiner Olliger's contributions to the field of lipopeptide deacylation exemplify the importance of innovation in biochemistry. His patented methods not only enhance our understanding of enzymatic processes but also pave the way for future advancements in biotechnology.